1082-183 The presence of chlamydia pneumoniae contributes to atherosclerotic plaque vulnerability
نویسندگان
چکیده
منابع مشابه
Chlamydia pneumoniae and atherosclerotic plaque.
To the Editor-According to Campbell et al. [1] in their recent study of Chlamydia pneumoniae in coronary tissue, staining with a Chlamydia-specific monoclonal antibody detected chlamydiae in 45% of the atherectomy specimens from patients with atherosclerotic plaque. However, staining appeared only in macrophages; smooth muscle cells did not stain, a result that appears to contradict previous fi...
متن کاملAssociation of Chlamydia pneumoniae Infection With Atherosclerotic Plaque Formation.
Atherosclerosis is a complex multifactorial disorder. Studies show that infectious microbial agents may play an important role in the development of atherosclerosis; however, these findings are conflicting. This study investigated the presence of Chlamydia pneumoniae DNA in atherosclerotic plaques of patients suffering from coronary artery disease. In a cross-sectional study, 85 patients (43 fe...
متن کاملPresence of Chlamydia pneumoniae in human symptomatic and asymptomatic carotid atherosclerotic plaque.
BACKGROUND Chlamydia pneumoniae has been identified in atherosclerotic plaques of patients with cerebrovascular and cardiovascular disease. However, the direct causative effect of C pneumoniae infection in the activation of atherosclerotic plaque to a prothrombotic state remains to be established. The aim of the present study is to examine the correlation between intraplaque presence of chlamyd...
متن کاملChlamydia pneumoniae and symptomatic carotid atherosclerotic plaque: a prospective study.
OBJECTIVE To investigate the possible link between symptomatic carotid atherosclerotic plaque and Chlamydia pneumoniae. BACKGROUND Recently, several studies have demonstrated that there may be a possible link between Chlamydia pneumonia and carotid atherosclerosis, however the real role of Chlamydia pneumoniae is not completely understood. METHOD This is a prospective study with a total of ...
متن کاملChlamydia pneumoniae in atherosclerotic tissue.
The majority of almost 30 publications from 1992 to 1999 describe Chlamydia pneumoniae organisms in atherosclerotic lesions of various major arteries. In the first study in the United Kingdom, C. pneumoniae was found in the aorta and femoral and iliac arteries. In a subsequent study, the organism was detected in arteries of subjects as young as 15 years. In a collaborative investigation, 71% of...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2004
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(04)92017-7